Ether crosses the placenta and reaches the fetus within a few minutes, achieving a steadystate concentration. In other words, there is no ether in petroleum ether. Diethyl ether is considered a good organic extracting solvent because it has a low polarity, according to the university of albertas organic web chem. Diethyl ether material safety data sheet cas no 60297 sdsmsds. Page 1 of 2 diethyl ether university of michiganflint. Diethyl ether is used in laboratory reagents, gasoline and diesel engine starting fluids, liniments and analgesics painkillers and smokeless gun powder. It is commonly used as a solvent in laboratories and as a starting fluid for some engines. But overdose of diethyl ether can cause respiratory paralysis and also result in death. Material safety data sheet section 1 chemical product and company identification msds name. Global product strategy gps safety summary diethyl ether. One advantage is a welldefined margin between therapeutic and toxic doses, which means one would lose consciousness before dangerous levels of dissolved ether in blood. Material safety data sheet petroleum ether msds number.
Cornell university, peroxideforming chemicals, retrieved april 2008. Synonyms for petrolem ether include naphtha, petroleum benzin. Material balances design project manufacture of diethyl ether diethyl ether dee is a colorless, highly volatile, flammable liquid with a characteristic odor. This msds has been prepared according to the hazard criteria of the controlled products regulations cpr and the msds contains all of the information required by the regulations. The actions of general anaesthetics diethyl ether, enflurane, isoflurane, methoxyflurane. Benzyl1napthyl ether 2,2diethoxypropane nmethylphenetole 1,2bis2chloroethoxylethane diethyl ethoxymethylenemalonate 2methyltetrahydrofuran bis2ethoxyethyl ether diethyl fumarate 3methoxy1butyl acetate bis2methoxyethoxyethyl ether diethyl acetal 2methoxyethanol bis2chloroethyl ether diethylketene 3methoxyethyl acetate. Ethers and peroxide forming compounds university of western. Ethyl ether in surface water will be subject to rapid volatilization with estimated halflives of 3.
Hazardous in case of skin contact irritant, of eye contact irritant, of ingestion, of inhalation. Triethylene glycol 97 112276 2039532 c 6 h 14 o 4 150. Chemical product and company identification product name. Ethanol is mixed with a strong acid like sulfuric acid h 2 so 4. Standard operating procedure for diethyl ether ether. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. Quantal analysis used software written by dr andrew jenkins cornell university. It is a colorless, highly volatile flammable liquid. For comparison, the vp of water at 20o centigrade is 17. Most diethyl ether is produced as a byproduct of the vaporphase hydration of ethylene to make ethanol. The handling of this chemical may incur notable safety precautions. It is highly recommended that you seek the material safety datasheet for this chemical from a reliable source such as siri, and follow its directions.
Repeated exposure may cause skin dryness or cracking. Page 1 of 8 msds oxalic acid material safety data sheet msds oxalic acid 1. Since diethyl ether can be used as an anesthetic, it is an appealing recreational drug. The substance identity section is calculated from substance identification information from all echa databases. Chemical product and company identification flammable gas mixture. Ethers are the most commonly used peroxide formers at wcm such as tetrahydrofuran, dioxane, diethyl ether, isopropyl ether. Als environmental does not sell chemicals, but offers analytical lab testing to determine the presence of various elements and chemical compounds.
Cornell university home environment, health and safety. Ether is an organic compound in which two carbon atoms are linked through an oxygen atom coc. Material safety data sheet diisopropyl ether extrapure. An ether may be a product of the condensation of alcohols. One disadvantage is the high flammability, especially in conjunction with oxygen. Material safety data sheet product name airgas inc. Check availability and compare product details diethyl ether chromasolv, for hplc, inhibitorfree. Easily soluble in cold water, hot water, methanol, diethyl ether, noctanol, acetone. Firstaid measures eyes rinse with plenty of water for at least 15 minutes and seek medical attention immediately.
The vp of vaseline a nonvolatile substance would be close to zero mm hg, while the vp of diethyl ether a very volatile substance is 440 mm hg. Diethyl ether is probably the most commonly employed solvent for the extraction of clomiphene 14,16, for instance, clomiphene was extracted from 3 ml of plasma in 1 ml borate buffer, ph 9, with an extraction efficiency of 70% at 30 ngml 14 clomiphene isomers, in addition to. Ghs classification in accordance with 29 cfr 1910 osha hcs. Pictogram signal word danger hazard statements h224 extremely flammable liquid and vapour. Diethyl ether is rarely prepared in laboratories because of the hazards involved and the easy availability to legitimate labs. Safety data sheet ghs product identifier other means of. Msds for diethyl ether is available at mallinckrodt baker structure and properties. It is basically a controlled substance and can be inhaled by the users to induce euphoria and sedation. Cdc niosh pocket guide to chemical hazards ethyl ether. Diethyl ether production process with various catalyst type.
The substance is of low molecular weight and is considered to be extremely flammable. It is an important solvent in the production of cellulose acetate and other cellulosebased polymers. Safety data sheet creation date 22sep2009 revision date 18jan2018 revision number 4 1. Ether is a volatile liquid thats vapors act as an anaesthetic when inhaled. Ph eur, diethyl ether, emprove essential ph eur,bp, diethyl ether, emplura, diethyl ether, for analysis emparta acs, diethyl ether, for gas chromatography ecd and fid suprasolv. Supplemental hazard statements euh019 may form explosive peroxides.
Overexposure to dimethyl ether may cause the following health effects. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Diethyl ether can be prepared both in laboratories and on an industrial scale by the process called acid ether synthesis. Acgih threshold limit values diethyl ether 60297 pel. Mcleish, in analytical profiles of drug substances and excipients, 1998. Material safety data sheet diethylamine pure section 1 section 1 chemical product and company identification msds name. Other uses for dee are as a starter fluid for diesel and gasoline engines, and as a. Refer to appendix a for a list of typical peroxide formers found at wcm and guidance on safe storage and testing frequency. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy.
Safety data sheet northwest missouri state university. Diethyl ether has a chemical formula of c 4 h 10 o and a molecular mass of 74. Industrial production of diethyl ether from ethanol. Understanding the safety risks of diethyl ether msdsonline. It is also used in agricultural and pharmaceutical applications. Diethyl ether material safety data sheet cas no 60297. It has been used both medically and recreationally since the late 1800s.
The most significant hazard associated with dimethyl ether is inhalation of vapors. If seeking medical attention provide sds document to physician. Ac148400025 casno 103504 synonyms dibenzyl ether recommended use laboratory chemicals. Accidental release measures immediately contact emergency personnel. Diethyl ether may react violently with halogens or strong oxidizers e.
The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas. When utilizing extraction solvents for liquidliquid extraction, two solvents must be used. Ether also refers loosely to diethyl ether, a colorless, volatile, highly inflammable liquid used in industry and biomedical research, and historically important as an anesthetic agent. Diethyl ether 60297 100 toxicological data on ingredients. The actions of ether, alcohol and alkane general anaesthetics on. These chemicals must be stabilized or decontaminated and discarded within 3 months of.
Ethyl ether will not significantly photooxidize via reaction with photochemically produced hydroxyl radicals in the water. The term petroleum ether is an old term used to refer to a mixture of hydrocarbons with a specific boiling point range. Its hazards and safe use ether diethyl ether, ethyl ether is an extremely common solvent that is routinely used in varying quantity in laboratory procedures through out the university, it is however a substance that has extreme physical hazards cognisance of which must always be a priority when planning even the. Epa, 1990 lists a chronic rfd for diethyl ether of 0. Vp is measured in units of millimeters of mercury mm hg. Diethyl ether safety data sheet according to federal register vol.
Symptoms of such overexposure to dimethyl ether can produce anesthetic effects sleepiness, loss of coordination, fatigue, as well as headaches, dizziness, nausea, and unconsciousness. This process uses solidsupported phosphoric acid catalysts and can be adjusted to make more ether if the need arises. A registration number is not available for this substance as the substance. No data availablebis2ethoxyethyl ether specific target organ toxicity repeated exposure no data available aspiration hazard no data availablebis2ethoxyethyl ether additional information rtecs. Diethyl ether in anesthetic dosage is an inhalant which has a long history of recreational use. Safety data sheet ethyl ether bdh1121 page 8 15 version 1. Safety data sheet according to 29cfr19101200 and ghs rev. Apr 27, 2015 learn more about diethyl ether safety due to its severe health risks, this chemical must be disposed of in strict accordance with federal, state, and local environmental control regulations. Smartlab indonesia msds diethyl ether page 2 material safety data sheet diethyl ether revision. Using peroxide test strips, check for peroxides upon opening a can of ether that is over a year old and every six months thereafter.
Hazards identification potential acute health effects. Diethyl ether, or simply ether, is an organic compound in the ether class with the formula c 2 h 5 2 o, sometimes abbreviated as et 2 o see pseudoelement symbols. Uses advised against food, drug, pesticide or biocidal product use. Diethyl ether, 60297, high purity solvents, c2h52o by loba chemie, india. Diethyl ether can form explosive peroxides upon storage in. At ambient temperature diethyl ether is a colorless liquid with a sweet, pungent odor. Symptoms include itching, burning, redness and tearing. Find out more about this and other chemicals in your workplace by browsing our database of msds information. Acros organics bvba janssen pharmaceuticalaan 3a 2440 geel, belgium company identification. Material balances design project manufacture of diethyl ether. The structure of diethyl ether is ch 3ch 2och 2ch 3, with the ballandstick model as. Diethyl ether cas no 60297 material safety data sheet sdsmsds. Material safety data sheet diethyl ether msds finar limited.
If medical advice is needed, have product container or label at hand. Also note that diethylether and petroleum ether are different substances. It is colorless but has a strong, distinct smell and a hot, sweet taste. Physical properties of diethyl ether5 property value cas number 60297 molecular weight 74. It was formerly used as a general anesthetic, until nonflammable drugs. Uses of ethers in health care industry, medical field. Repeated or extended contact may cause erythema reddening of the skin or dermatitis, resulting from a defatting action on tissue.
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